Nimesulide Induced Histopathological Changes in the Vas Deferens of Mice
نویسندگان
چکیده
منابع مشابه
Nimesulide induced histopathological changes in the vas deferens of mice.
AIM Nimesulide, a preferential COX-2 inhibitor has 20 times more selectivity towards COX-2 than that of COX-1. COX-2 selective inhibitors cause frequent nephrotoxicity and hepatotoxicity following their usage. This proposes a physiological role of COX-2 in kidney and liver. Not much attention has been focused on the role of COX-2 with respect to reproduction especially in male reproduction, and...
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The relaxatory effect of Vitis vinifera leaf extract on rat uterus has been reported and it was postulated that, the extract relaxed through the blockade of voltage dependent calcium channels. The extract also, relaxed rat aorta through NO and was dependent on the functional endothelium. In the present study, the effect of Vitis vinifera hydroalcoholic leaf extract (VHLE) on rat vas deferens pr...
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متن کاملRat vas deferens relaxation induced by Vitis vinifera leaf extract
The relaxatory effect of Vitis vinifera leaf extract on rat uterus has been reported and it was postulated that, the extract relaxed through the blockade of voltage dependent calcium channels. The extract also, relaxed rat aorta through NO and was dependent on the functional endothelium. In the present study, the effect of Vitis vinifera hydroalcoholic leaf extract (VHLE) on rat vas deferens pr...
متن کاملMitigating effects of Jambul against lead induced toxicity in epididymis and vas deferens of mice
BACKGROUND Precious fruits like jambul are neglected and wasted while environmental pollutants like lead intake remain overlooked. OBJECTIVE The aim of this study was to investigate the effects of the Jambul pulp extract on lead detrimental effects in pseudostratified epithelium and the stereocilia of mice epididymis and vas deferens. MATERIALS AND METHODS Thirty young males mice (Mus muscu...
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ژورنال
عنوان ژورنال: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
سال: 2013
ISSN: 2249-782X
DOI: 10.7860/jcdr/2013/6693.3446